Effects of Supplementation With Iron, Selenium and Magnesium on Galleria mellonella Cell-Mediated Immune Responses

Immune responses play a key role in the survival of all living things. Intake inorganic materials is critical importance organisms because their participation metabolism and some component cells. Iron (Fe), magnesium (Mg) selenium (Se) were selected for this study constituents cells, such as nucleic acids enzymes organisms, indirect direct effects on immunity. Although separate these are known, there no combined effects. Galleria mellonella, which used model organism, frequently evaluating human pathogens due to its various properties. Total hemocyte counts encapsulation-melanization most commonly observed parameters when examining immune organism. In our study, added ratio 0.1%, 0.25%, 0.5% 1% nutrient content mellonella organism investigated. As result it was found that only 0.25% doses increased count other significantly decreased compared control group. However, determined feeding caused significant decrease both responses. According findings, nutrients have over certain dose by substances negative